The Complexity of Malignant Glioma Treatment

Author

Izuchukwu Nwachukwu
July 02, 2025

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The Complexity of Malignant Glioma Treatment

This article focuses on the multifaceted and deeply challenging aspect of modern oncology: the treatment of malignant gliomas, particularly glioblastoma. It unravels how the tumor’s microenvironment, cellular adaptability, and intricate interactions with immune cells and the brain itself make therapy not only difficult but elusive. Rather than proposing a single silver bullet, it examines a layered treatment model targeting several dynamic “hallmarks” of cancer through repurposed drugs, immunotherapies, and precision strategies tailored to each patient.

But as this complex puzzle unfolds with aggressive tumors, stealthy stem-like cells, and a battlefield of immune evasion, one can’t help but ask: what if the very brain that harbors the tumor holds the key to its destruction?

The Complexity of Malignant Glioma Treatment.pdf5.02 MB • PDF File

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